Effectiveness of Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis (Wegener's)
نویسندگان
چکیده
منابع مشابه
Effectiveness of rituximab for the otolaryngologic manifestations of granulomatosis with polyangiitis (Wegener's).
OBJECTIVE Ear, nose, and throat (ENT) involvement is the most prevalent manifestation of granulomatosis with polyangiitis (Wegener's) (GPA) and correlates with permanent damage and decreased quality of life. Although prior studies have evaluated the efficacy of rituximab (RTX) for granulomatous features of GPA, none have evaluated its efficacy solely for ENT manifestations. We compared the effe...
متن کاملENT manifestations of Wegeners granulomatosis.
Wegeners granulomatosis is a necrotizing granulomatous vasculitis with multisystemic involvement. We present two cases of Wegener's presenting with otological manifestations as the first symptom. These symptoms are subtle and diagnosis may be easily overlooked. Hence a high index of suspicion is required. Early diagnosis and treatment goes a long way in improving the outcomes and in preventing ...
متن کاملPulmonary manifestations of granulomatosis with polyangiitis.
OBJECTIVE To describe the clinical and laboratory data, with special emphasis on thoracic imaging findings, in 14 patients with a definitive diagnosis of granulomatosis with polyangiitis (GPA). METHODS The clinical and tomographic data of 14 patients with a definitive diagnosis of GPA are presented. Patients with thoracic manifestations suggestive of GPA were evaluated in 3 hospitals from 200...
متن کاملGranulomatosis and polyangiitis: the rituximab option.
Over the subsequent month, she developed swollen and painful knees and left ankle, a rash over her legs, and red eyes. She denied fever, chills, headache, past sinusitis, chest pain, dyspnea, abdominal pain or diarrhea. Her physical examination disclosed signs of synovitis in her knees and left ankle, palpable purpura over her legs and scleral erythema suggestive of episcleritis. The blood test...
متن کاملAn Unusual Presentation of Granulomatosis with Polyangiitis
The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN). The antinuclear (ANA) and...
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ژورنال
عنوان ژورنال: Arthritis Care & Research
سال: 2014
ISSN: 2151-464X
DOI: 10.1002/acr.22311